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VOL. 10, ISSUE 1 (2025)
Development and characterization of gastroretentive mucoadhesive tablet as controlled release system: A review
Authors
Abhijit Anand, Priyanka Rani, Jatin Preet Kaur, Gazzal Mehta, Dr. Jagtar Singh Chohan
Abstract
Gastroretentive mucoadhesive tablets are a promising controlled drug
delivery system designed to enhance the retention time of medications in the
stomach. This approach helps improve the effectiveness of drugs that are
intended to act locally in the gastric region or are absorbed primarily in the
upper gastrointestinal tract. This thesis explores the various polymers used in
the formulation of mucoadhesive tablets, examining their role in promoting
adhesion to the gastric mucosa. Additionally, it discusses the key factors
influencing mucoadhesion, such as the properties of the polymers, the pH of the
gastric environment, and the composition of the dosage form. The thesis also
reviews recent advancements in techniques for evaluating and characterizing
mucoadhesive tablets, including in vitro methods that assess their
performance and stability.
Pages:1-5
How to cite this article:
Abhijit Anand, Priyanka Rani, Jatin Preet Kaur, Gazzal Mehta, Dr. Jagtar Singh Chohan "Development and characterization of gastroretentive mucoadhesive tablet as controlled release system: A review". International Journal of Pharmaceutical Science and Research, Vol 10, Issue 1, 2025, Pages 1-5
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